Welcome to EvoNiche



EvoNiche is a comprehensive database developed to enable comprehensive analysis of spatial patterns and heterogeneity, spatiotemporal evolutionary trajectories, and spatial cell-cell interactions, integrating multi-dimensional spatial omics data with advanced analytical frameworks for delineating the dynamic architecture of tumor ecosystems.


Overview Design
Overview Design
Region Dynamics
Page 1
RegionCell

Deciphering cellular composition and spatial distribution in tumor/stromal regions

Page 2
RegionGene

Iidentifying region-specific gene expression signatures

Page 5
RegionFunction

Discovering region-specific biological functions

Page 6
RegionLR

Characterizing ligand-receptor spatial heterogeneity

Spatiotemporal Dynamics
Page 3
PSMCell

Illustrating cell subpopulations distribution along spatial-temporal trajectory

Page 4
PSMGene

Identifying transition genes with dynamic expression patterns

Page 7
PSMFunction

Revealing functional dynamics across pseudo-spatiotemporal map

Page 8
PSMLR

Elucidating spatiotemporal evolution of the ligand-receptor interaction network.